Scale-Up of Integrated Biorefineries and Greenhouse Gas Reduction in First Generation Ethanol Production (Scale-Up+) - American Cities Climate Challenge
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Scale-Up of Integrated Biorefineries and Greenhouse Gas Reduction in First Generation Ethanol Production (Scale-Up+)

Federal Agency


Bioenergy Technologies Office (BETO)


To support high-impact technology RD&D to accelerate the bioeconomy and, in particular, the production of low-carbon fuels for the aviation, marine, rail, and long-haul trucking industries; to strengthen current first generation (Gen-1) corn ethanol production facilities by reducing their overall carbon footprint.

Applicant and/or Project Eligibility Requirements

Broad eligibility for groups, governments, individuals, and consortia of the above, including alllowances for foreign entities. BETO is interested in the following Topic Areas: - TA 1: Pre-Pilot Scale-Up of Integrated Biorefineries - TA 2: Pilot Scale-Up of Integrated Biorefineries - TA 3: Demonstration Scale-Up of Integrated Biorefineries - TA 4: Gen-1 Corn Ethanol Emission Reduction

Decarbonization Considerations

BETO focuses on developing technologies that convert domestic lignocellulosic biomass and waste resources into affordable low-carbon biofuels and bioproducts that significantly reduce carbon emissions on a life-cycle basis as compared to equivalent petroleum-based products. By reducing cost and technicl risk, BETO helps the industry deploy commercial-scale integrated biorefineries and reduce greenhouse gas emissions from hard-to-decarbonize sectors, such as the aviation industry. This FOA will support the Biden Administration’s new action items to produce 3 billion gallons of sustainable aviation fuel (SAF) per year and reduce aviation emissions by 20% by 2030 towards unlocking the potential for a fully zero-carbon aviation sector by 2050.

Equity Considerations

Applicants are required to submit a Diversity, Equity, and Inclusion Plan that describes the actions the applicant will take to foster a welcoming and inclusive environment, support people from underrepresented groups in STEM, advance equity, and encourage the inclusion of individuals from these groups in the project; and the extent the project activities will be located in or benefit underserved communities.

Helpful Tips

BETO is focusing on applied RD&D to improve the performance and reduce cost of biofuel production technologies and scale-up production systems in partnership with industry. BETO is focused on developing and demonstrating technologies that are capable of producing low-carbon, cost-effective biofuels and co-products by 2030, as well as biofuel production pathways that can deliver at least 70% lower lifecycle greenhouse gas emissions than petroleum.

Other Notes


Deadline (Announced or Anticipated)

Concept Paper due July 8, 2022 Application due September 9, 2022

Funding Available


Max Award Amount


Expected Allocations

4-20 total

Average Award (Estimated)

Varies by subtopic

Matching Funds

20-50% cost share, depending on subtopic

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